Rakhi Thambi MD, MBA Chief Ambulatory Medical Officer | University Of Illinois Hospital - Chicago
Rakhi Thambi MD, MBA Chief Ambulatory Medical Officer | University Of Illinois Hospital - Chicago
More than one million American women of childbearing age are living with epilepsy, facing unique challenges related to hormonal changes, reproductive health, and bone density. There is a growing acknowledgment that the standard treatment for epilepsy should be tailored to meet women's specific needs.
UI Health, a leading Level 4 Epilepsy Center, is committed to providing personalized care by considering patients' health and lifestyle goals. The center supports women throughout all stages of life. Dr. Anna Serafini, director of the Women with Epilepsy Program at UI Health, emphasizes the importance of specialized care that understands and adapts to the distinct needs of women with epilepsy.
"Understanding how hormones interact with the brain to influence seizures is crucial for effective management," says Dr. Serafini. She highlights that tracking menstrual cycles can reveal patterns that help tailor treatment plans in alignment with hormonal changes.
Women with epilepsy must also consider contraception carefully due to interactions between anti-seizure medications (ASMs) and hormonal birth control, which can affect effectiveness and lead to breakthrough seizures. "Through collaboration and coordinated care with UI Health OB-GYN providers, our Epilepsy team ensures that each woman’s contraceptive plan supports both her reproductive and epilepsy needs," states Dr. Serafini.
Family planning poses additional challenges for women with epilepsy due to misconceptions about pregnancy risks and fertility. Despite these challenges, women with epilepsy can have healthy pregnancies and babies. "It is crucial for women with epilepsy to plan their pregnancies to optimize seizure control and ensure the safest outcomes," advises Dr. Serafini.
Bone health is another concern as certain epilepsy medications may reduce calcium and vitamin D absorption, increasing osteoporosis risk—especially during menopause. Regular bone scans and supplements are recommended as part of a proactive approach.
The impact of seizures extends beyond physical health, affecting daily life activities such as driving, employment, memory, mood, and family responsibilities. "We understand how much a seizure can change a person’s lifestyle," notes Dr. Serafini.
UI Health aims to bridge gaps in standard care by offering gender-specific epilepsy treatment adapted to women's lifestyles and health needs.
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